这是新系统的一大弊端。
This is the one major drawback of the new system.
他们用许多难懂的大词。
They use a lot of big words.
保健已经成为大生意。
Health and fitness have become big business.
这婚礼可是一大盛典。
The wedding was a great occasion.
他们要养活一大家人。
They have a large family to feed.
我钓的鱼有这么大呢。
The fish I caught was yay big.